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COMPLEMENT FACTOR D
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DeCS
Descriptor
English
:
Complement Factor D
Descriptor
Spanish
:
Factor D del Complemento
Descriptor
Portuguese
:
Fator D do Complemento
Synonyms
English
:
Adipsin
C3 Convertase Activator
C3PA Convertase
Factor D
Properdin Factor D
Tree Number:
D08.811.277.300.450
D08.811.277.656.300.760.200
D08.811.277.656.959.350.200
D12.776.124.486.274.045.450
Definition
English
:
A
serum
protein which is important in the ALTERNATIVE
COMPLEMENT ACTIVATION
PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound
COMPLEMENT FACTOR B
to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE.
Indexing Annotation
English
:
see SCR for organism-specific terms
Pharmacological Action:
Immunologic Factors
History Note
English
:
1999 (1978)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
23520
Unique Identifier:
D011416
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS